Related references
Note: Only part of the references are listed.GATOR1-dependent recruitment of FLCN-FNIP to lysosomes coordinates Rag GTPase heterodimer nucleotide status in response to amino acids
Jin Meng et al.
JOURNAL OF CELL BIOLOGY (2018)
Review: Mechanistic target of rapamycin (mTOR) pathway, focal cortical dysplasia and epilepsy
E. Marsan et al.
NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY (2018)
A nutrient-induced affinity switch controls mTORC1 activation by its Rag GTPase-Ragulator lysosomal scaffold
Rosalie E. Lawrence et al.
NATURE CELL BIOLOGY (2018)
Intersubunit Crosstalk in the Rag GTPase Heterodimer Enables mTORC1 to Respond Rapidly to Amino Acid Availability
Kuang Shen et al.
MOLECULAR CELL (2017)
The Dawn of the Age of Amino Acid Sensors for the mTORC1 Pathway
Rachel L. Wolfson et al.
CELL METABOLISM (2017)
mTOR Signaling in Growth, Metabolism, and Disease
Robert A. Saxton et al.
CELL (2017)
Recurrent mTORC1-activating RRAGC mutations in follicular lymphoma
Jessica Okosun et al.
NATURE GENETICS (2016)
Dynamic Visualization of mTORC1 Activity in Living Cells
Xin Zhou et al.
CELL REPORTS (2015)
Spatial Control of the TSC Complex Integrates Insulin and Nutrient Regulation of mTORC1 at the Lysosome
Suchithra Menon et al.
CELL (2014)
The Folliculin Tumor Suppressor Is a GAP for the RagC/D GTPases That Signal Amino Acid Levels to mTORC1
Zhi-Yang Tsun et al.
MOLECULAR CELL (2013)
A Tumor Suppressor Complex with GAP Activity for the Rag GTPases That Signal Amino Acid Sufficiency to mTORC1
Liron Bar-Peled et al.
SCIENCE (2013)
Crystal Structure of the Gtr1pGTP-Gtr2pGDP Protein Complex Reveals Large Structural Rearrangements Triggered by GTP-to-GDP Conversion
Jae-Hee Jeong et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2012)
Ragulator-Rag Complex Targets mTORC1 to the Lysosomal Surface and Is Necessary for Its Activation by Amino Acids
Yasemin Sancak et al.
CELL (2010)
The Rag GTPases bind raptor and mediate amino acid signaling to mTORC1
Yasemin Sancak et al.
SCIENCE (2008)
Mutations in a novel gene lead to kidney tumors, lung wall defects, and benign tumors of the hair follicle in patients with the Birt-Hogg-Dube syndrome
ML Nickerson et al.
CANCER CELL (2002)
Share Paper
