Journal
NATURE CELL BIOLOGY
Volume 16, Issue 6, Pages 502-504Publisher
NATURE PUBLISHING GROUP
DOI: 10.1038/ncb2984
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Funding
- NCI NIH HHS [P30 CA008748] Funding Source: Medline
- NICHD NIH HHS [R01 HD052115] Funding Source: Medline
- NIDDK NIH HHS [R01 DK084391] Funding Source: Medline
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Pluripotent embryonic stem cells (ESCs) can be derived from blastocyst-stage mouse embryos. However, the exact in vivo counterpart of ESCs has remained elusive. A combination of expression profiling and stem cell derivation identifies epiblast cells from late-stage blastocysts as the source, and functional equivalent, of ESCs.
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