Related references
Note: Only part of the references are listed.Notch signaling: switching an oncogene to a tumor suppressor
Camille Lobry et al.
BLOOD (2014)
The Ubiquitin Ligase FBXW7 Modulates Leukemia-Initiating Cell Activity by Regulating MYC Stability
Bryan King et al.
CELL (2013)
Postinduction Dexamethasone and Individualized Dosing of Escherichia Coli L-Asparaginase Each Improve Outcome of Children and Adolescents With Newly Diagnosed Acute Lymphoblastic Leukemia: Results From a Randomized Study-Dana-Farber Cancer Institute ALL Consortium Protocol 00-01
Lynda M. Vrooman et al.
JOURNAL OF CLINICAL ONCOLOGY (2013)
Activation of the canonical IKK complex by K63/M1-linked hybrid ubiquitin chains
Christoph H. Emmerich et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)
The genetic basis of early T-cell precursor acute lymphoblastic leukaemia
Jinghui Zhang et al.
NATURE (2012)
Dysregulation of CDK8 and Cyclin C in tumorigenesis
Wu Xu et al.
JOURNAL OF GENETICS AND GENOMICS (2011)
PHYSIOLOGICAL RELEVANCE OF CELL CYCLE KINASES
Marcos Malumbres
PHYSIOLOGICAL REVIEWS (2011)
Exome Sequencing of Head and Neck Squamous Cell Carcinoma Reveals Inactivating Mutations in NOTCH1
Nishant Agrawal et al.
SCIENCE (2011)
The Mutational Landscape of Head and Neck Squamous Cell Carcinoma
Nicolas Stransky et al.
SCIENCE (2011)
Inactivation of LEF1 in T-cell acute lymphoblastic leukemia
Alejandro Gutierrez et al.
BLOOD (2010)
Phosphorylation by Casein Kinase I Promotes the Turnover of the Mdm2 Oncoprotein via the SCFβ-TRCP Ubiquitin Ligase
Hiroyuki Inuzuka et al.
CANCER CELL (2010)
CDK8 is a positive regulator of transcriptional elongation within the serum response network
Aaron J. Donner et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2010)
Nuclear CDKs Drive Smad Transcriptional Activation and Turnover in BMP and TGF-β Pathways
Claudio Alarcon et al.
CELL (2009)
The human CDK8 subcomplex is a molecular switch that controls Mediator coactivator function
Matthew T. Knuesel et al.
GENES & DEVELOPMENT (2009)
Prognostic Implications of NOTCH1 and FBXW7 Mutations in Adults With T-Cell Acute Lymphoblastic Leukemia Treated on the MRC UKALLXII/ECOG E2993 Protocol
Marc R. Mansour et al.
JOURNAL OF CLINICAL ONCOLOGY (2009)
Cell Cycle Regulatory Effects of Retinoic Acid and Forskolin Are Mediated by the Cyclin C Gene
Katri M. Makkonen et al.
JOURNAL OF MOLECULAR BIOLOGY (2009)
Phosphorylation by Cyclin C/Cyclin-Dependent Kinase 2 following Mitogenic Stimulation of Murine Fibroblasts Inhibits Transcriptional Activity of LSF during G1 Progression
Utsav H. Saxena et al.
MOLECULAR AND CELLULAR BIOLOGY (2009)
Cell cycle, CDKs and cancer: a changing paradigm
Marcos Malumbres et al.
NATURE REVIEWS CANCER (2009)
Leukemia-associated NOTCH1 alleles are weak tumor initiators but accelerate K-ras-initiated leukemia
Mark Y. Chiang et al.
JOURNAL OF CLINICAL INVESTIGATION (2008)
Oncogenesis of T-ALL and nonmalignant consequences of overexpressing intracellular NOTCH1
Xiaoyu Li et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2008)
E2F1 represses β-catenin transcription and is antagonized by both pRB and CDK8
Erick J. Morris et al.
NATURE (2008)
CDK8 is a colorectal cancer oncogene that regulates β-catenin activity
Ron Firestein et al.
NATURE (2008)
FBW7 ubiquitin ligase: a tumour suppressor at the crossroads of cell division, growth and differentiation
Markus Welcker et al.
NATURE REVIEWS CANCER (2008)
Notch-1 mutations are secondary events in some patients with T-Cell acute lymphoblastic leukemia
Marc R. Mansour et al.
CLINICAL CANCER RESEARCH (2007)
Evaluation of malignant and benign gastric biopsy specimens by mRNA expression profile and multivariate statistical methods
Orsolya Galamb et al.
CYTOMETRY PART B-CLINICAL CYTOMETRY (2007)
Identification of genomic classifiers that distinguish induction failure in T-lineage acute lymphoblastic leukemia: a report from the Children's Oncology Group
Stuart S. Winter et al.
BLOOD (2007)
The SCFFBW7 ubiquitin ligase complex as a tumor suppressor in T cell leukemia
Benjamin J. Thompson et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2007)
CDK8 is a stimulus-specific positive coregulator of p53 target genes
Aaron Joseph Donner et al.
MOLECULAR CELL (2007)
A kinase subunit of the human mediator complex, CDK8, positively regulates transcriptional activation
Tadashi Furumoto et al.
GENES TO CELLS (2007)
The cyclin-dependent kinase 8 module sterically blocks Mediator interactions with RNA polymerase II
Hans Elmlund et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)
Identification of a conserved negative regulatory sequence that influences the leukemogenic activity of NOTCH1
Mark Y. Chiang et al.
MOLECULAR AND CELLULAR BIOLOGY (2006)
Notch1 mutations are important for leukemic transformation in murine models of precursor-T leukemia/lymphoma
YW Lin et al.
BLOOD (2006)
High incidence of Notch-1 mutations in adult patients with T-cell acute lymphoblastic leukemia
MR Mansour et al.
LEUKEMIA (2006)
Activating Notch1 mutations in mouse models of T-ALL
J O'Neil et al.
BLOOD (2006)
Expression and gene amplification of primary (A, B1, D1, D3, and E) and secondary (C and H) cyclins in colon adenocarcinomas and correlation with patient outcome
J Bondi et al.
JOURNAL OF CLINICAL PATHOLOGY (2005)
Cyclin C/Cdk3 promotes Rb-dependent G0 exit
SJ Ren et al.
CELL (2004)
Mastermind recruits CycC:CDK8 to phosphorylate the notch ICD and coordinate activation with turnover
CJ Fryer et al.
MOLECULAR CELL (2004)
A fluorescence in situ hybridization map of 6q deletions in acute lymphocytic leukemia: Identification and analysis of a candidate tumor suppressor gene
PB Sinclair et al.
CANCER RESEARCH (2004)
Activating mutations of NOTCH1 in human T cell acute lymphoblastic leukemia
AP Weng et al.
SCIENCE (2004)
Exploration, normalization, and summaries of high density oligonucleotide array probe level data
RA Irizarry et al.
BIOSTATISTICS (2003)
Notch1 functions as a tumor suppressor in mouse skin
M Nicolas et al.
NATURE GENETICS (2003)
Srb10/Cdk8 regulates yeast filamentous growth by phosphorylating the transcription factor Ste12
C Nelson et al.
NATURE (2003)
Defining the region(s) of deletion at 6q16-q22 in human prostate cancer
ER Hyytinen et al.
GENES CHROMOSOMES & CANCER (2002)
Negative regulation of Gcn4 and Msn2 transcription factors by Srb10 cyclin-dependent kinase
Y Chi et al.
GENES & DEVELOPMENT (2001)
A premature-termination mutation in the Mus musculus cyclin-dependent kinase 3 gene
X Ye et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2001)
TFIIH is negatively regulated by cdk8-containing mediator complexes
S Akoulitchev et al.
NATURE (2000)
Mapping of target regions of allelic loss in primary breast cancers to 1-cM intervals on genomic contigs at 6q21 and 6q25.3
Y Utada et al.
JAPANESE JOURNAL OF CANCER RESEARCH (2000)
Share Paper
