Journal
NATURE CELL BIOLOGY
Volume 14, Issue 12, Pages 1244-1245Publisher
NATURE PUBLISHING GROUP
DOI: 10.1038/ncb2634
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Regulation of organ size is achieved through the action of the mTOR and Hippo signalling pathways, which control cell proliferation and cell growth in response to extracellular cues. A link between these pathways is revealed by the finding that YAP downregulates PTEN to promote cell growth and tissue hyperplasia.
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