Journal
NATURE CELL BIOLOGY
Volume 13, Issue 9, Pages 1016-1023Publisher
NATURE PUBLISHING GROUP
DOI: 10.1038/ncb2329
Keywords
-
Categories
Funding
- NIH [R01 DK080425, 1P01CA120964]
- American Cancer Society
- American Diabetes Association
- Howard Hughes Medical Institute
Ask authors/readers for more resources
One of the central regulators of cellular and organismal metabolism in eukaryotes is AMP-activated protein kinase (AMPK), which is activated when intracellular ATP production decreases. AMPK has critical roles in regulating growth and reprogramming metabolism, and has recently been connected to cellular processes such as autophagy and cell polarity. Here we review a number of recent breakthroughs in the mechanistic understanding of AMPK function, focusing on a number of newly identified downstream effectors of AMPK.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available