4.8 Editorial Material

Wnt signalling escapes to cilia

Journal

NATURE CELL BIOLOGY
Volume 13, Issue 6, Pages 636-637

Publisher

NATURE PUBLISHING GROUP
DOI: 10.1038/ncb0611-636

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Funding

  1. Grants-in-Aid for Scientific Research [21247034] Funding Source: KAKEN

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The primary cilium is proposed to restrain the level of canonical Wnt signalling, but it was unknown how the cilium achieves this. beta-catenin,a component of the canonical Wnt signalling pathway, is now shown to be sequestered to the cilium by the Wnt signalling modulator Jouberin (Jbn) to restrain Wnt responses.

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