4.8 Editorial Material

HIF hits Wnt in the stem cell niche

Journal

NATURE CELL BIOLOGY
Volume 12, Issue 10, Pages 926-927

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NATURE PUBLISHING GROUP
DOI: 10.1038/ncb1010-926

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distinct stem-cell populations are known to reside in hypoxic niches during development and postnatal life. Hypoxia-inducible transcription factors (HIFs) directly regulate the Wnt/beta-catenin pathway to ensure the maintenance of both adult and embryonic stem cells.

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