Journal
NATURE CELL BIOLOGY
Volume 11, Issue 9, Pages 1053-1054Publisher
NATURE PUBLISHING GROUP
DOI: 10.1038/ncb0909-1053
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Funding
- NICHD NIH HHS [P01 HD070494] Funding Source: Medline
- NINDS NIH HHS [R01 NS048453] Funding Source: Medline
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Aurora A, an integral mitotic kinase, is essential for microtubule dynamics of post-mitotic neurons. PKC zeta activates Aurora A, which in turn phosphorylates NDEL1 to promote neurite extension. This raises the possibility that Aurora A may also be involved in establishing cell polarity and axon/dendrite elaboration in young neurons.
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