Related references
Note: Only part of the references are listed.CasOT: a genome-wide Cas9/gRNA off-target searching tool
An Xiao et al.
BIOINFORMATICS (2014)
A systematic analysis of recombination activity and genotype-phenotype correlation in human recombination-activating gene 1 deficiency
Yu Nee Lee et al.
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY (2014)
CRISPR-Cas systems for editing, regulating and targeting genomes
Jeffry D. Sander et al.
NATURE BIOTECHNOLOGY (2014)
Genome editing with Cas9 in adult mice corrects a disease mutation and phenotype
Hao Yin et al.
NATURE BIOTECHNOLOGY (2014)
Broad specificity profiling of TALENs results in engineered nucleases with improved DNA-cleavage specificity
John P. Guilinger et al.
NATURE METHODS (2014)
A guide to genome engineering with programmable nucleases
Hyongbum Kim et al.
NATURE REVIEWS GENETICS (2014)
Developmental propagation of V(D)J recombination-associated DNA breaks and translocations in mature B cells via dicentric chromosomes
Jiazhi Hu et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2014)
IgH class switching exploits a general property of two DNA breaks to be joined in cis over long chromosomal distances
Monica Gostissa et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2014)
One-Step Generation of Mice Carrying Reporter and Conditional Alleles by CRISPR/Cas-Mediated Genome Engineering
Hui Yang et al.
CELL (2013)
Identification of Early Replicating Fragile Sites that Contribute to Genome Instability
Jacqueline H. Barlow et al.
CELL (2013)
Double Nicking by RNA-Guided CRISPR Cas9 for Enhanced Genome Editing Specificity
F. Ann Ran et al.
CELL (2013)
Mechanisms of Programmed DNA Lesions and Genomic Instability in the Immune System
Frederick W. Alt et al.
CELL (2013)
Mapping genomic hotspots of DNA damage by a single-strand-DNA-compatible and strand-specific ChIP-seq method
Zhi-Xiong Zhou et al.
GENOME RESEARCH (2013)
CAS9 transcriptional activators for target specificity screening and paired nickases for cooperative genome engineering
Prashant Mali et al.
NATURE BIOTECHNOLOGY (2013)
DNA targeting specificity of RNA-guided Cas9 nucleases
Patrick D. Hsu et al.
NATURE BIOTECHNOLOGY (2013)
Knockout mice created by TALEN-mediated gene targeting
Young Hoon Sung et al.
NATURE BIOTECHNOLOGY (2013)
High-throughput profiling of off-target DNA cleavage reveals RNA-programmed Cas9 nuclease specificity
Vikram Pattanayak et al.
NATURE BIOTECHNOLOGY (2013)
High-frequency off-target mutagenesis induced by CRISPR-Cas nucleases in human cells
Yanfang Fu et al.
NATURE BIOTECHNOLOGY (2013)
RNA-guided editing of bacterial genomes using CRISPR-Cas systems
Wenyan Jiang et al.
NATURE BIOTECHNOLOGY (2013)
RNA-Guided Human Genome Engineering via Cas9
Prashant Mali et al.
SCIENCE (2013)
Multiplex Genome Engineering Using CRISPR/Cas Systems
Le Cong et al.
SCIENCE (2013)
YAHA: fast and flexible long-read alignment with optimal breakpoint detection
Gregory G. Faust et al.
BIOINFORMATICS (2012)
Spatial Organization of the Mouse Genome and Its Role in Recurrent Chromosomal Translocations
Yu Zhang et al.
CELL (2012)
FLASH assembly of TALENs for high-throughput genome editing
Deepak Reyon et al.
NATURE BIOTECHNOLOGY (2012)
TAL Effector-Nucleotide Targeter (TALE-NT) 2.0: tools for TAL effector design and target prediction
Erin L. Doyle et al.
NUCLEIC ACIDS RESEARCH (2012)
A Programmable Dual-RNA-Guided DNA Endonuclease in Adaptive Bacterial Immunity
Martin Jinek et al.
SCIENCE (2012)
Translocation-Capture Sequencing Reveals the Extent and Nature of Chromosomal Rearrangements in B Lymphocytes
Isaac A. Klein et al.
CELL (2011)
Genome-wide Translocation Sequencing Reveals Mechanisms of Chromosome Breaks and Rearrangements in B Cells
Roberto Chiarle et al.
CELL (2011)
A TALE nuclease architecture for efficient genome editing
Jeffrey C. Miller et al.
NATURE BIOTECHNOLOGY (2011)
An unbiased genome-wide analysis of zinc-finger nuclease specificity
Richard Gabriel et al.
NATURE BIOTECHNOLOGY (2011)
Molecular basis of engineered meganuclease targeting of the endogenous human RAG1 locus
Ines G. Munoz et al.
NUCLEIC ACIDS RESEARCH (2011)
A novel TALE nuclease scaffold enables high genome editing activity in combination with low toxicity
Claudio Mussolino et al.
NUCLEIC ACIDS RESEARCH (2011)
Targeted Genome Editing Across Species Using ZFNs and TALENs
Andrew J. Wood et al.
SCIENCE (2011)
Targeting DNA Double-Strand Breaks with TAL Effector Nucleases
Michelle Christian et al.
GENETICS (2010)
Frequent Endonuclease Cleavage at Off-target Locations In Vivo
Lisa M. Petek et al.
MOLECULAR THERAPY (2010)
Circos: An information aesthetic for comparative genomics
Martin Krzywinski et al.
GENOME RESEARCH (2009)
Complex landscapes of somatic rearrangement in human breast cancer genomes
Philip J. Stephens et al.
NATURE (2009)
Mechanisms of change in gene copy number
P. J. Hastings et al.
NATURE REVIEWS GENETICS (2009)
Cellular responses to DNA double-strand breaks after low-dose γ-irradiation
Aroumougame Asaithamby et al.
NUCLEIC ACIDS RESEARCH (2009)
Model-based Analysis of ChIP-Seq (MACS)
Yong Zhang et al.
GENOME BIOLOGY (2008)
High-resolution insertion-site analysis by linear amplification-mediated PCR (LAM-PCR)
Schmidt Manfred et al.
NATURE METHODS (2007)
The impact of translocations and gene fusions on cancer causation
Felix Mitelman et al.
NATURE REVIEWS CANCER (2007)
Role of genomic instability and p53 in AID-induced c-myc-Igh translocations
AR Ramiro et al.
NATURE (2006)
H2AX prevents DNA breaks from progressing to chromosome breaks and translocations
S Franco et al.
MOLECULAR CELL (2006)
Share Paper
