Journal
NATURE
Volume 559, Issue 7715, Pages 490-497Publisher
NATURE PORTFOLIO
DOI: 10.1038/s41586-018-0318-5
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Funding
- Medical Research Council
- National Institute of Health Research Health Protection Research Unit programme
- National Institute of General Medical Sciences 'MIDAS' programme
- Bill and Melinda Gates Foundation
- MRC [MR/R015600/1] Funding Source: UKRI
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Mosquito-borne diseases remain a major cause of morbidity and mortality across the tropical regions. Despite much progress in the control of malaria, malaria-associated morbidity remains high, whereas arboviruses-most notably dengue-are responsible for a rising burden of disease, even in middle-income countries that have almost completely eliminated malaria. Here I discuss how new interventions offer the promise of considerable future reductions in disease burden. However, I emphasize that intervention programmes need to be underpinned by rigorous trials and quantitative epidemiological analyses. Such analyses suggest that the long-term goal of elimination is more feasible for dengue than for malaria, even if malaria elimination would offer greater overall health benefit to the public.
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