Journal
NATURE
Volume 559, Issue 7715, Pages 484-485Publisher
NATURE PUBLISHING GROUP
DOI: 10.1038/d41586-018-05573-4
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Funding
- MRC [MC_UU_12022/6] Funding Source: UKRI
- Medical Research Council [MC_UU_12022/6] Funding Source: Medline
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Clinical use of the anticancer drug methotrexate can be limited by its high toxicity. It emerges that a diet rich in the amino acid histidine increases the effectiveness of methotrexate treatment and lowers toxicity in mice.
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