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Metabolism of stromal and immune cells in health and disease

Journal

NATURE
Volume 511, Issue 7508, Pages 167-176

Publisher

NATURE PUBLISHING GROUP
DOI: 10.1038/nature13312

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Funding

  1. FWO
  2. Marie Curie Fellowship
  3. Flemish Government, FWO [IUAP P7/03]
  4. AXA Research Fund
  5. ERC Advanced Research Grant

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Cancer cells have been at the centre of cell metabolism research, but the metabolism of stromal and immune cells has received less attention. Nonetheless, these cells influence the progression of malignant, inflammatory and metabolic disorders. Here we discuss the metabolic adaptations of stromal and immune cells in health and disease, and highlight how metabolism determines their differentiation and function.

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