4.8 Review

Genetics and pathogenesis of inflammatory bowel disease

Related references

Note: Only part of the references are listed.
Article Medicine, Research & Experimental

Loss of intestinal core 1-derived O-glycans causes spontaneous colitis in mice

Jianxin Fu et al.

JOURNAL OF CLINICAL INVESTIGATION (2011)

Article Immunology

IL-27 promotes T cell-dependent colitis through multiple mechanisms

Jennifer H. Cox et al.

JOURNAL OF EXPERIMENTAL MEDICINE (2011)

Article Immunology

NFIL3 Is a Regulator of IL-12 p40 in Macrophages and Mucosal Immunity

Taku Kobayashi et al.

JOURNAL OF IMMUNOLOGY (2011)

Article Multidisciplinary Sciences

Reduction of disulphide bonds unmasks potent antimicrobial activity of human β-defensin 1

Bjoern O. Schroeder et al.

NATURE (2011)

Article Multidisciplinary Sciences

Genetic susceptibility to systemic lupus erythematosus protects against cerebral malaria in mice

Michael Waisberg et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)

Article Multidisciplinary Sciences

Induction of Colonic Regulatory T Cells by Indigenous Clostridium Species

Koji Atarashi et al.

SCIENCE (2011)

Article Genetics & Heredity

Human ITCH E3 Ubiquitin Ligase Deficiency Causes Syndromic Multisystem Autoimmune Disease

Naomi J. Lohr et al.

AMERICAN JOURNAL OF HUMAN GENETICS (2010)

Article Medicine, General & Internal

Penetrance of NOD2/CARD15 genetic variants in the general population

Shiva Yazdanyar et al.

CANADIAN MEDICAL ASSOCIATION JOURNAL (2010)

Article Immunology

Milk sialyllactose influences colitis in mice through selective intestinal bacterial colonization

Andrea Fuhrer et al.

JOURNAL OF EXPERIMENTAL MEDICINE (2010)

Article Immunology

Identification of an Autophagy Defect in Smokers' Alveolar Macrophages

Martha M. Monick et al.

JOURNAL OF IMMUNOLOGY (2010)

Article Immunology

LRRK2 Is Involved in the IFN-γ Response and Host Response to Pathogens

Agnes Gardet et al.

JOURNAL OF IMMUNOLOGY (2010)

Article Multidisciplinary Sciences

Gut inflammation provides a respiratory electron acceptor for Salmonella

Sebastian E. Winter et al.

NATURE (2010)

Article Multidisciplinary Sciences

Generation of pathogenic TH17 cells in the absence of TGF-β signalling

Kamran Ghoreschi et al.

NATURE (2010)

Article Multidisciplinary Sciences

A human gut microbial gene catalogue established by metagenomic sequencing

Junjie Qin et al.

NATURE (2010)

Article Genetics & Heredity

Association of IFIH1 and other autoimmunity risk alleles with selective IgA deficiency

Ricardo C. Ferreira et al.

NATURE GENETICS (2010)

Article Biochemistry & Molecular Biology

NOD2 stimulation induces autophagy in dendritic cells influencing bacterial handling and antigen presentation

Rachel Cooney et al.

NATURE MEDICINE (2010)

Article Multidisciplinary Sciences

Endoplasmic reticulum stress-induced transcription factor, CHOP, is crucial for dendritic cell IL-23 expression

Jane C. Goodall et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)

Article Multidisciplinary Sciences

Induction and rescue of Nod2-dependent Th1-driven granulomatous inflammation of the ileum

Amlan Biswas et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)

Article Multidisciplinary Sciences

Slc15a4, AP-3, and Hermansky-Pudlak syndrome proteins are required for Toll-like receptor signaling in plasmacytoid dendritic cells

Amanda L. Blasius et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)

Article Multidisciplinary Sciences

Resolvin E1-induced intestinal alkaline phosphatase promotes resolution of inflammation through LPS detoxification

Eric L. Campbell et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)

Article Multidisciplinary Sciences

Induction of regulatory T cells by macrophages is dependent on production of reactive oxygen species

Marina D. Kraaij et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)

Article Multidisciplinary Sciences

Organismal, genetic, and transcriptional variation in the deeply sequenced gut microbiomes of identical twins

Peter J. Turnbaugh et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)

Article Multidisciplinary Sciences

MyD88 signaling in nonhematopoietic cells protects mice against induced colitis by regulating specific EGF receptor ligands

Katharina Brandl et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)

Article Multidisciplinary Sciences

Metabolic Syndrome and Altered Gut Microbiota in Mice Lacking Toll-Like Receptor 5

Matam Vijay-Kumar et al.

SCIENCE (2010)

Article Multidisciplinary Sciences

Reversible Microbial Colonization of Germ-Free Mice Reveals the Dynamics of IgA Immune Responses

Siegfried Hapfelmeier et al.

SCIENCE (2010)

Article Multidisciplinary Sciences

Association of Trypanolytic ApoL1 Variants with Kidney Disease in African Americans

Giulio Genovese et al.

SCIENCE (2010)

Review Oncology

Ipilimumab: Unleashing the Power of the Immune System Through CTLA-4 Blockade

Peter Boasberg et al.

SEMINARS IN ONCOLOGY (2010)

Article Microbiology

Potentiation of Epithelial Innate Host Responses by Intercellular Communication

Tamas Dolowschiak et al.

PLOS PATHOGENS (2010)

Article Biochemistry & Molecular Biology

Induction of Intestinal Th17 Cells by Segmented Filamentous Bacteria

Ivaylo I. Ivanov et al.

Article Immunology

STAT3 links IL-22 signaling in intestinal epithelial cells to mucosal wound healing

Geethanjali Pickert et al.

JOURNAL OF EXPERIMENTAL MEDICINE (2009)

Article Biochemistry & Molecular Biology

Hepatocyte Nuclear Factor 4α, a Key Factor for Homeostasis, Cell Architecture, and Barrier Function of the Adult Intestinal Epithelium

Anne-Laure Cattin et al.

MOLECULAR AND CELLULAR BIOLOGY (2009)

Article Multidisciplinary Sciences

A core gut microbiome in obese and lean twins

Peter J. Turnbaugh et al.

NATURE (2009)

Article Multidisciplinary Sciences

Regulation of inflammatory responses by gut microbiota and chemoattractant receptor GPR43

Kendle M. Maslowski et al.

NATURE (2009)

Article Immunology

Activation of innate immune antiviral responses by Nod2

Ahmed Sabbah et al.

NATURE IMMUNOLOGY (2009)

Article Medicine, General & Internal

Inflammatory Bowel Disease and Mutations Affecting the Interleukin-10 Receptor

Erik-Oliver Glocker et al.

NEW ENGLAND JOURNAL OF MEDICINE (2009)

Article Medicine, General & Internal

Genomewide Association Study of Leprosy

Fu-Ren Zhang et al.

NEW ENGLAND JOURNAL OF MEDICINE (2009)

Article Multidisciplinary Sciences

Enhanced sensitivity to DSS colitis caused by a hypomorphic Mbtps1 mutation disrupting the ATF6-driven unfolded protein response

Katharina Brandl et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)

Article Multidisciplinary Sciences

Many human large intergenic noncoding RNAs associate with chromatin-modifying complexes and affect gene expression

Ahmad M. Khalil et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)

Article Multidisciplinary Sciences

Identification of Splenic Reservoir Monocytes and Their Deployment to Inflammatory Sites

Filip K. Swirski et al.

SCIENCE (2009)

Article Gastroenterology & Hepatology

Epidemiology of inflammatory bowel disease in a German twin cohort: Results of a nationwide study

Martina E. Spehlmann et al.

INFLAMMATORY BOWEL DISEASES (2008)

Article Multidisciplinary Sciences

A microbial symbiosis factor prevents intestinal inflammatory disease

Sarkis K. Mazmanian et al.

NATURE (2008)

Article Genetics & Heredity

Deletion polymorphism upstream of IRGM associated with altered IRGM expression and Crohn's disease

Steven A. McCarroll et al.

NATURE GENETICS (2008)

Article Multidisciplinary Sciences

Faecalibacterium prausnitzii is an anti-inflammatory commensal bacterium identified by gut microbiota analysis of Crohn disease patients

Harry Sokol et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)

Article Biochemistry & Molecular Biology

Communicable ulcerative colitis induced by T-bet deficiency in the innate immune system

Wendy S. Garrett et al.

Article Multidisciplinary Sciences

Molecular-phylogenetic characterization of microbial community imbalances in human inflammatory bowel diseases

Daniel N. Frank et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)

Article Multidisciplinary Sciences

A short isoform of NOD2/CARD15, NOD2-S, is an endogenous inhibitor of NOD2/receptor-interacting protein kinase 2-induced signaling pathways

P Rosenstiel et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)