Journal
NATURE
Volume 455, Issue 7215, Pages 903-911Publisher
NATURE PUBLISHING GROUP
DOI: 10.1038/nature07456
Keywords
-
Categories
Funding
- National Institute of Mental Health
- Simon Foundation
Ask authors/readers for more resources
The brain processes information by transmitting signals at synapses, which connect neurons into vast networks of communicating cells. In these networks, synapses not only transmit signals but also transform and refine them. Neurexins and neuroligins are synaptic cell- adhesion molecules that connect presynaptic and postsynaptic neurons at synapses, mediate signalling across the synapse, and shape the properties of neural networks by specifying synaptic functions. In humans, alterations in genes encoding neurexins or neuroligins have recently been implicated in autism and other cognitive diseases, linking synaptic cell adhesion to cognition and its disorders.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available