Journal
NATURAL PRODUCT RESEARCH
Volume 28, Issue 15, Pages 1147-1151Publisher
TAYLOR & FRANCIS LTD
DOI: 10.1080/14786419.2014.918122
Keywords
gorgonian; Menella kanisa Grassoff; sesquiterpene; structure elucidation
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Funding
- National Natural Science Foundation of China [81172977]
- National High Technology Research and Development Program of China (863 Program) [2013AA093001]
- Natural Science Foundation of Shandong Province [ZR2011DQ019]
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Chemical investigation of the gorgonian Menella kanisa Grassoff collected from the South China Sea led to the isolation of a new sesquiterpene, menecubebane A (1), together with three known compounds, 8-methoxy-trans-calamenene (2), 8,9-dihydro-linderazulene (3) and (3)-oleanan-3-ol (4). The structure of 1 was determined by detailed analysis of the spectroscopic data especially the NOESY spectrum. All the compounds were evaluated for their cytotoxic, brine shrimp lethal and antifouling activities.
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