Journal
NATURAL PRODUCT RESEARCH
Volume 27, Issue 21, Pages 2055-2058Publisher
TAYLOR & FRANCIS LTD
DOI: 10.1080/14786419.2013.811660
Keywords
Rosa soulieana; antioxidants; ABTS; phenolics; flavonoids; phenylpropanoid glycosides
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Funding
- Main Direction Program of the Knowledge Innovation Project of CAS [KSCX2-EW-J-22]
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Rosa soulieana has been widely used in traditional medicine to treat cardiovascular disorders. In this study, antioxidant activity-guided fractionation and purification of the methanol extract from the flowers of R. soulieana has led to the isolation of nine phenolic antioxidants, which were identified as catechin (1), tiliroside (2), astragalin (3), isoquercitrin (4), nicotiflorin (5), eugenol 4-O--d-(6-O-galloyl) glucoside (6), michehedyosides D (7), citrusin C (8) and strictinin (9), respectively. Among them, compounds 5-9 were reported from the genus Rosa for the first time. All the compounds were also assayed by in vitro ABTS [2,2-azinobis(3-ethylbenzothiazoline-6-sulphonic acid) diammonium salt] radical cation scavenging activity. Among these bioactive isolates (1-9), compounds 1, 6, 7 and 9 exhibited strong scavenging activity in ABTS (SC50=10.17, 7.38, 8.60, 4.72mol/L, respectively) compared with the positive control l-ascorbic acid (SC50=15.97mol/L).
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