Journal
NATURAL PRODUCT RESEARCH
Volume 28, Issue 1, Pages 7-11Publisher
TAYLOR & FRANCIS LTD
DOI: 10.1080/14786419.2013.827191
Keywords
gorgonian; Ellisella dollfusi; briarane; diterpenoid; structure elucidation; bioactivity
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Funding
- National Natural Science Foundation of China [41130858, 41176121, 81172977]
- National High Technology Research and Development Program of China (863 Program) [2013AA093001]
- Natural Science Foundation of Shandong Province [ZR2011DQ019, ZR2011HM085]
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Two new briarane-type diterpenoids, dollfusilin A (1) and dollfusilin B (2), along with five known briarane-type diterpenoids (3-7), were isolated from the gorgonian Ellisella dollfusi collected from the South China Sea. The structures of the two new compounds (1 and 2) were elucidated through a comprehensive analysis of spectroscopic data, especially 2D NMR. The bioactivities of the isolated compounds were evaluated using the zebrafish toxicity model.
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