Journal
NATURAL PRODUCT RESEARCH
Volume 26, Issue 1, Pages 66-71Publisher
TAYLOR & FRANCIS LTD
DOI: 10.1080/14786419.2010.535160
Keywords
Cariniana; HPLC; NMR; triterpenes; antioxidant; antifungal
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The Lecythidaceae family is composed of 25 genera and 400 species that occur in the form of trees with a pantropical distribution. The genera Cariniana belongs to the family Lecythidaceae, and there are few reports considering these species. In this work, fractionation of the dichloromethane fraction obtained from the aqueous extract of the stem bark of Cariniana domestica (Mart) Miers, popularly known as Jequitiba-roxo, led to the isolation of two mixtures of triterpenoids: lupeol and beta-amyrin and beta-sitosterol and stigmasterol. The structures of the isolated compounds were elucidated by spectroscopic (NMR) and chromatographic (GC-MS) techniques as well as literature data comparisons. beta-Sitosterol, stigmasterol, lupeol and beta-amyrin were quantified in dichloromethane fraction by high-performance liquid chromatography (HPLC/DAD). The dichloromethane fraction was also investigated for antioxidant and antifungal activities. The isolated compounds and their biological activities are reported for the first time for the species C. domestica.
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