Chemical constituents of Asplenium ruta-muraria L.

A phytochemical study of Asplenium ruta-muraria L. (Aspleniaceae) led to the isolation of a new caffeic acid glycoside, 2-O-caffeoyl-beta-D-fructofuranosyl-(2 -> 1)-alpha-D-glucopyranoside and an (alpha, beta)-isomeric pair of 2E-caffeoyl-D-glucopyranoside, together with kaempferol-3-O-beta-D-[6-E-caffeoyl-beta-D-glucopyranosyl-(1 -> 2)glucopyranoside]-7-O-beta-D-glucopyranoside, 1-O-caffeoyl glycoside, sucrose, diploptene and beta-sitosterol. Their structures were established by means of MS and capillary NMR techniques. Additionally, aromatase inhibitory activity of the extracts and phenolic compounds was evaluated.