Journal
NATURAL PRODUCT RESEARCH
Volume 26, Issue 10, Pages 926-932Publisher
TAYLOR & FRANCIS LTD
DOI: 10.1080/14786419.2010.534991
Keywords
Periploca sepium Bunge; 2-hydroxy-4-methoxy-benzaldehyde; Drosophila melanogaster L.; essential oil; Sitophilus zeamais Motsch.; contact toxicity
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Funding
- Hi-Tech Research and Development of China [2006AA10A209]
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During our screening programme for agrochemicals from Chinese medicinal herbs, the root bark essential oil of Periploca sepium was found to possess strong contact toxicity against the fruit flies, Drosophila melanogaster with a LD50 value of 1.22 mu g/adult. The main component of the essential oil was identified to be 2-hydroxy-4-methoxy-benzaldehyde (78.8%), followed by linalool (2.8%) and (-)-alpha-terpineol (2.7%). The 2-hydroxy-4-methoxy-benzaldehyde was further isolated and identified by bioassay-directed fractionation. The compound showed strong contact toxicity against D. melanogaster and the maize weevil (Sitophilus zeamais) with LD50 values of 1.47 and 6.99 mu g/adult, respectively.
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