Journal
NATURAL PRODUCT RESEARCH
Volume 26, Issue 8, Pages 770-773Publisher
TAYLOR & FRANCIS LTD
DOI: 10.1080/14786419.2011.561435
Keywords
Piper chimonantifolium; chromene; flavonoids; steroids; antifungal activity
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Funding
- CNPq
- FAPESP
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In this study, the CH2Cl2 extract from leaves of Piper chimonantifolium was subjected to several chromatographic separation procedures to afford one chromene (gaudichaudianic acid) as a major compound as well as two flavonoids (dihydrooroxylin and pinocembrin) and three steroids (sitosterol, sitosteryl palmitate and stigmasterol). The structures of all determined compounds were characterised by spectrometric analysis, mainly mass spectrometry and NMR, as well as their optical properties. This article describes the first phytochemical study of the leaves of P. chimonantifolium and an evaluation of the antifungal activity of its major compounds.
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