Journal
NATURAL PRODUCT RESEARCH
Volume 25, Issue 8, Pages 857-862Publisher
TAYLOR & FRANCIS LTD
DOI: 10.1080/14786419.2010.536159
Keywords
Prosopis cineraria; Ehrlich ascites carcinoma; haematological studies; invitro cytotoxicity; life span; solid tumour
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The antitumour activity of the hydroalcoholic extract of the leaf (PCL) and stem bark (PCB) of Prosopis cineraria (L.) in Swiss albino mice was evaluated against an Ehrlich ascites carcinoma (EAC) tumour model. The activity was assessed using survival time, peritoneal cells, haematological studies, lipid peroxidation, antioxidant enzymes such as superoxide dismutase, catalase, glutathione peroxidase, glutathione S-transferase, solid tumour mass and invitro cytotoxicity. PCL and PCB were found to be potent and possessed significant cytotoxicity towards EAC tumour cells.
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