Journal
NATURAL PRODUCT RESEARCH
Volume 25, Issue 9, Pages 898-904Publisher
TAYLOR & FRANCIS LTD
DOI: 10.1080/14786419.2010.509722
Keywords
seaweeds; jolynamine; spectroscopy; anti-microbial activity
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Funding
- US Office of Naval Research [N 00014-86-G-0229, NP-14]
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A new compound, jolynamine (1), was isolated from the marine brown alga Jolyna laminarioides collected from the coast of Karachi, Pakistan. In addition, four known compounds, namely saringosterol (2), loliolide (3), methyl-4-hydroxybenzoate (4) and propyl-4-hydroxybenzoate (5), were isolated for the first time from the marine brown alga Iyengaria stellata, and two known compounds, namely 3,4,5-trimethylaniline (6) and harmine (7), were isolated for the first time from the marine brown alga Melanothamnus afaqhusainii. Compound 6 is synthetically known but was isolated for the first time from a natural source. The structures of these compounds were elucidated with the help of powerful spectroscopic techniques. Furthermore, the methanolic extracts of both algae showed anti-microbial activities against various bacteria and fungi.
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