Journal
NATURAL PRODUCT RESEARCH
Volume 25, Issue 6, Pages 585-591Publisher
TAYLOR & FRANCIS LTD
DOI: 10.1080/14786419.2010.485303
Keywords
polyoxygenated steroids; gorgosterol; NBT-T2; cytotoxicity
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Funding
- University of Ryukyus
- Ministry of Education, Culture, Sports, Science and Technology (MEXT), Japan [18032061]
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Four new polyoxygenated steroids (1-4) together with four known ones (5-8) have been isolated from the gorgonian Isis hippuris. The structures of the new compounds have been elucidated by spectroscopic analysis and chemical conversion. All of the new steroids showed moderate cytotoxicity against cultured NBT-T2 cells.
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