4.4 Article

Four new polyoxygenated gorgosterols from the gorgonian Isis hippuris

Journal

NATURAL PRODUCT RESEARCH
Volume 25, Issue 6, Pages 585-591

Publisher

TAYLOR & FRANCIS LTD
DOI: 10.1080/14786419.2010.485303

Keywords

polyoxygenated steroids; gorgosterol; NBT-T2; cytotoxicity

Funding

  1. University of Ryukyus
  2. Ministry of Education, Culture, Sports, Science and Technology (MEXT), Japan [18032061]

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Four new polyoxygenated steroids (1-4) together with four known ones (5-8) have been isolated from the gorgonian Isis hippuris. The structures of the new compounds have been elucidated by spectroscopic analysis and chemical conversion. All of the new steroids showed moderate cytotoxicity against cultured NBT-T2 cells.

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