Journal
NATURAL PRODUCT RESEARCH
Volume 24, Issue 6, Pages 569-579Publisher
TAYLOR & FRANCIS LTD
DOI: 10.1080/14786410902899915
Keywords
Vitex agnus-castus L; supercritical extraction; hydrodistillation; antifungal activity
Categories
Funding
- NATURALMENTE SARDEGNA [Progetto PON 1.4L-2006-16]
Ask authors/readers for more resources
Isolation of volatile concentrates from leaves, flowers and fruits of Vitex agnus-castus L. have been obtained by supercritical extraction with carbon dioxide. The composition of the volatile concentrates has been analysed by GC/MS. In all plant organs, the extracts are composed chiefly of -pinene, sabinene, 1,8-cineole, -terpinyl acetate, (E)-caryophyllene, (E)--farnesene, bicyclogermacrene, spathulenol and manool. The main difference observed was in the content of sclarene, which was not present in the samples from flowers or fruits. To complete the investigation, a comparison with the hydrodistilled oil has been carried out. The minimal inhibitory concentration (MIC) and the minimal lethal concentration were used to evaluate the antifungal activity of the oils against dermatophyte strains (Trichophyton mentagrophytes, Microsporum canis, T. rubrum, M. gypseum and Epidermophyton floccosum). Antifungal activity of the leaf essential oil was the highest, with MIC values of 0.64 mu L mL-1 for most of the strains.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available