4.4 Article

A new antioxidant flavonoid from the lianas of Gnetum macrostachyum

Journal

NATURAL PRODUCT RESEARCH
Volume 23, Issue 16, Pages 1472-1477

Publisher

TAYLOR & FRANCIS LTD
DOI: 10.1080/14786410802280943

Keywords

Gnetum macrostachyum; Gnetaceae; 5,7,2 '-trihydroxy-5 '-methoxyflavone; antioxidation

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A new flavonoid, named 5,7,2'-trihydroxy-5'-methoxyflavone (1), was isolated from the acetone extract of the lianas of Gnetum macrostachyum together with 5,7,4'-trihydroxy-3'-methoxyflavanone (2) and seven known stilbenoids (3-7). The structure of the new compound was determined by interpretation of its spectral data and chemical transformation. The isolated compounds showed radical scavenging activity against DPPH with IC50 values in the range of 0.21-19.90mM.

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