Journal
NATURAL PRODUCT RESEARCH
Volume 23, Issue 7, Pages 607-612Publisher
TAYLOR & FRANCIS LTD
DOI: 10.1080/14786410802114068
Keywords
Anabaena constricta; antimicrobial activity; cyanobacteria; exometabolite; brominated indole alkaloid
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A new brominated indole alkaloid, designated as bromoanaindolone, was isolated from culture media of the cyanobacterium Anabaena constricta and was identified as 6-bromo-3-hydroxy-3-methyl-indol-2-one with a slight excess of the (3R) enantiomer. The molecular structure was elucidated on the basis of IR, MS and NMR data. This extracellular metabolite of A. constricta possessed antimicrobial (anticyanobacterial and antibacterial) activity in different test systems, such as suspension and porous matrix tests.
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