Secondary metabolites of Aspergillus sp F1, a commensal fungal strain of Trewia nudiflora

Twelve compounds that belonged to five structure types, namely saturated dibenzylbutyrolactone lignans (1-3), sesterterpenoids (4-6), anthraquinone (questin, 7), benzophenone (dihydrogeodin, 8) and diphenyl ethers (9-12), were isolated from the extract of the strain Aspergillus sp. F1, which was isolated from the seeds of Trewia nudiflora. Among them, compounds 1, 11 and 12 were determined to be new, namely butylrolactone-V, butyl 2,4-dichloroasterrate and methyl 2,4-dichloroasterrate, respectively. The structures of these compounds were characterised on the basis of spectroscopic data.