4.4 Article

Macrolactin S, a novel macrolactin antibiotic from marine Bacillus sp.

Journal

NATURAL PRODUCT RESEARCH
Volume 22, Issue 4, Pages 342-347

Publisher

TAYLOR & FRANCIS LTD
DOI: 10.1080/14786410701768162

Keywords

Bacillus sp.; macrolactin S; antibacterial

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A new 24-membered ring lactone, macrolactin S, was isolated from a culture broth of marine Bacillus sp. and its structure was established by various spectral analyses. Macrolactin S is the first macrolactin hydroxylated at C-12. Besides, the known compounds macrolactin A and macrolactin B were also isolated, which were elucidated on the basis of spectral data analyses and literature data comparison. They exhibited antibacterial activity against E. coli and S. aureus.

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