Two new flavonoids from Origanum vulgare

In addition to the major constituents apigenin, luteolin, salvagenin, cirsimartin, diosmetin, desmethoxycentauridin, 5-hydroxy-6,7,3',4'-tetramethoxy-abigenin, apigenin 7-O-glucoside, luteolin 7-O-glucoside, luteolin 7-O-glucoside-6''-methylester, two new flavonoids were isolated, in minor concentration, and identified as luteolin 7-O--L-rhamnoside-4'-O--D-glucoside and quercetin 3-O--D-glucoside-4'-O--L-rhamnoside from the methanolic extract of Origanum vulgare L. The structures were determined by conventional analytical methods and confirmed by MS and NMR spectral analysis.