A new cytotoxic acylated apigenin glucoside from Phyllanthus emblica L.

A new acylated apigenin glucoside (apigenin-7-O-(6 ''-butyryl-beta-glucopyranoside) (1) was isolated from the methanolic extract of the leaves of Phyllanthus emblica L. (Euphorbiaceae) together with the known compounds; gallic acid (2), methyl gallate (3), 1,2,3,4,6-penta-O-galloylglucose (4) and luteolin-4'-O-neohesperiodoside (5). Their chemical structures were elucidated on the basis of spectroscopic studies (H-1 NMR, C-13 NMR, DEPT, HSQC, HMBC).