4.7 Review

Antibiotics from myxobacteria

Journal

NATURAL PRODUCT REPORTS
Volume 31, Issue 7, Pages 953-972

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/c4np00011k

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Funding

  1. German Research Association (DFG Research Unit) [FOR 854]
  2. German Centre for Infection Research (DZIF)

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Myxobacteria produce a vast range of structurally diverse natural products with prominent biological activities. Here, we provide a detailed description and judge the potential of all antibiotically active myxobacterial compounds as lead structures, pointing out their particularities and, if known, their mode of action. Thus, the review provides an overview of the potential of specific compounds, suitable for future investigations and possible clinical applications.

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