Rocaglamide, silvestrol and structurally related bioactive compounds from Aglaia species

Investigations on the chemistry and biology of rocaglamide, silvestrol and structurally related bioactive compounds from Aglaia species during the period 2006-2013 are reviewed. Included are new phytochemical studies of naturally occurring rocaglamide derivatives, an update on synthetic methods for cyclopenta[b] benzofurans, and a description of the recent biological evaluation and mechanism-of-action studies on compounds of this type.