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Natural products and Chagas' disease: a review of plant compounds studied for activity against Trypanosoma cruzi

Journal

NATURAL PRODUCT REPORTS
Volume 28, Issue 4, Pages 809-823

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/c0np00069h

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Funding

  1. Conselho Nacional de Desenvolvimento Cientifico e Tecnologico - CNPq
  2. Capacitacao de Aperfeicoamento de Pessoal de Nivel Superior - CAPES
  3. Financiadora de Estudos e Projetos - FINEP
  4. PRONEX/Fundacao Araucaria
  5. INCT_if
  6. Programa de Posgraduacao em Microbiologia da Universidade Estadual de Londrina

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Here, we review studies that have investigated the activity of plant-derived compounds against Trypanosoma cruzi, the etiologic agent of Chagas' disease. In the last decade, more than 300 species belonging to almost 100 families have been evaluated for activity, and here we describe the compounds isolated; 85 references are cited.

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