Journal
NATURAL PRODUCT REPORTS
Volume 28, Issue 1, Pages 15-25Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/c0np00044b
Keywords
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Funding
- NIH-NIGMS [GM086483]
- NATIONAL INSTITUTE OF GENERAL MEDICAL SCIENCES [R01GM086483] Funding Source: NIH RePORTER
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Chlorosulfolipids have been isolated from freshwater algae and from toxic mussels. They appear to have a structural role in algal membranes and have been implicated in Diarrhetic Shellfish Poisoning. Further fascinating aspects of these compounds include their stereochemically complex polychlorinated structures and the resulting strong conformational biases, and their poorly understood (yet surely compelling) biosynthesis. Discussions of each of these topics and of efforts in structural and stereochemical elucidation and synthesis are the subject of this Highlight.
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