Journal
NATURAL PRODUCT REPORTS
Volume 27, Issue 12, Pages 1840-1870Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/c0np00031k
Keywords
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Funding
- National S & T Major Project [2009ZX09301-001, 2009ZX09103-060]
- National S & T marine 863 projects [2007AA09Z447, 2007AA09Z402]
- Natural Science Foundation of China [30730108, 20721003, 40976048, 81072572]
- STCSM [09ZR1438000, 10540702900]
- CAS [SIMM0907KF-09, KSCX2-YW-R-18]
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The spirodioxynaphthalenes are a group of fungal secondary metabolites, consisting of a 1,8-dihydroxynaphthalene-derived spiroketal unit linked to a second oxidized naphthalene moiety, that show a great variety of biological activities. This review summarizes the research on the isolation, structure elucidation, biological activities, biosynthesis, and chemical synthesis of the spirodioxynaphthalenes published over the last 20 years. More than 100 fungal and plant metabolites are described, and over 100 references cited.
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