4.7 Review

Asymmetric organocatalysis in total synthesis - a trial by fire

Journal

NATURAL PRODUCT REPORTS
Volume 27, Issue 8, Pages 1138-1167

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/b924964h

Keywords

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Funding

  1. DFG [SPP1179]
  2. Fonds der Chemischen Industrie (Dozentenstipendium)
  3. Alexander von Humboldt Stiftung
  4. Fundacion Aragon I + D
  5. Consejo Superior de Investigaciones Cientificas CSIC [PIE 200880I260]
  6. Ministerio de Ciencia e Innovacion (MICINN) [CTQ2009-09028]
  7. Aragon Government [PI064/09]

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This review covers the most recent applications of organocatalysis in the synthesis of natural products and non-natural biologically active molecules. Our aim is to showcase how organocatalytic reactions have overcome some of their teething problems and how they frequently offer very practical solutions to long-standing synthetic challenges. 161 references are cited.

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