Effect of Garlic Extract on Haematobiochemical Changes in Eimeria tenella Infected Broiler Chicken

Present study was conducted to evaluate the effect of garlic extract on coccidia induced haematobiochemical alterations in broiler chicken. For this study, 144, day old white strain chicks were reared under strict hygienic condition. At the age of 14 days these chicks were randomly divided into three groups-I, II and III, each containing 48 chicks. Group I chicks served as control, while group II chicks were administered 9 x 10(4) sporulated oocysts of field strain of Eimeria tenella and group III chicks were administered same dose of sporulated oocysts of E. tenella and were fed garlic extract at the rate of 0.5 ml per bird per day orally. For hematological study blood from randomly selected 10 chicks in each group was collected at 7, 14, 21 and 28 DPI in EDTA containing test tubes. For biochemical tests blood was obtained without anticoagulant and serum was separated from coagulated blood for analysis. Haematological parameters showed significant decrease in Hb, PCV, TEC in group II and group III than control group birds while TLC and MCV revealed significant increase in group II and group III birds than control group birds. Garlic treated group birds revealed significant increase in Hb, PCV, TEC and significant decrease in TLC values than infected group birds from 7 DPI up to the end of study. Serum biochemistry revealed significant decreases in serum proteins, albumin and globulin values and significant increase in AST, ALT and creatinine levels in group II and group III birds than control group from 7 DPI up to last observation. A significant increase of serum proteins, albumin and globulin values and significant decrease in, AST, ALT and creatinine levels was observed in garlic treated group birds than infected group birds from 7 DPI up to last observation. Thus concluding E. tenella significantly deteriorated haematobiochemical parameters in chicken while garlic extract significantly improved these altered haematobiochemical values.