Journal
NANOTECHNOLOGY
Volume 24, Issue 32, Pages -Publisher
IOP PUBLISHING LTD
DOI: 10.1088/0957-4484/24/32/325103
Keywords
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Funding
- NANOMAT program of the Research Council of Norway [182058]
- South-Eastern Norway Regional Health Authority [20100068]
- Norwegian Radium Hospital Research Foundation [FU0802]
- Yggdrasil mobility programme of the Research Council of Norway [202676]
- US National Science Foundation [0967423]
- Directorate For Engineering
- Div Of Chem, Bioeng, Env, & Transp Sys [0967423] Funding Source: National Science Foundation
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Spherical carbon nanoparticles (carbon nanodots) with a silver shell were investigated as potential sensitizing agents. The cytotoxicity of the combination of ultraviolet radiation or x-rays with the nanodots was examined in cancer cells in vitro. The cell viability decreased following the exposure to the radiation. The carbon nanodots enhanced the radiation effects by significantly reducing the amount of surviving cells compared to that of the cells exposed only to the radiation. Carbon-core silver-shell nanodots can be proposed as a bimodal sensitization platform for biological and medicinal applications employing non-ionizing or ionizing radiation.
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