An Electrochemical Sensor Based on Reduced Graphene Oxide and ZnO Nanorods-Modified Glassy Carbon Electrode for Uric Acid Detection

In this paper, reduced graphene oxide-ZnO (RGO-ZnO) nanorods composite was prepared via a simple one-pot hydrothermal approach. The synthesized RGO-ZnO nanorods composite has been successfully applied for glassy carbon electrode (GCE) surface modification. The RGO-ZnO nanorods composite-modified GCE was applied for sensitive and selective determination of uric acid (UA). The biosensor exhibited a linear dependence on UA concentration ranging from 1 to 800 mu M with a detection limit of 0.312 mu M(S/N = 3). The proposed UA sensor also showed an excellent stability, reproducibility and anti-interference property.