4.6 Article

Label-free detection of amyloid growth with microcantilever sensors

Journal

NANOTECHNOLOGY
Volume 19, Issue 38, Pages -

Publisher

IOP PUBLISHING LTD
DOI: 10.1088/0957-4484/19/38/384007

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Funding

  1. Engineering and Physical Sciences Research Council [GR/R45680/01] Funding Source: researchfish
  2. Medical Research Council [qA137861b] Funding Source: researchfish

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We present an approach for sensing protein aggregation using microcantilever systems. Results from both single cantilever experiments with internal reference and multicantilever array measurements with dedicated reference cantilevers are discussed. We show that in both cases protein aggregation on the sensor can be detected through associated changes in surface stress.

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