Journal
NANOSCALE
Volume 10, Issue 15, Pages 6812-6819Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/c7nr08720a
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Funding
- National University of Singapore (NUS), Department of Pharmacy (AcRF Tier 1 FRC) [R-148-000-213-112]
- Leung Kai Fook grant [R-148000-227-720]
- NUS Graduate School for Integrative Sciences and Engineering
- Department of Pharmacy
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A hybrid drug delivery platform involving the fusion of cell membranes from U937 monocytes and synthetic lipids to create nano-cell vesicle technology systems (nCVTs) is designed. nCVTs are engineered for a targeted approach towards tumour sites by preserving key surface proteins from U937 monocytes, while being amendable to functionalization and loading due to their liposomal components.
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