Journal
NANOSCALE
Volume 6, Issue 8, Pages 4078-4082Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/c3nr06770j
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Funding
- National Institutes of Health [R01 EB006201, T32 EB001040, 5K08-NS075144-03, DP1 EB016986, R01 EB016963]
- Department of Defense (DOD) [W81XWH-09-1-0064]
- Defense Advanced Research Projects Agency [HR0011-13-2-0003]
- Duke Exploratory Research Funds
- National Children's Research Centre (NCRC) Funds
- NATIONAL CANCER INSTITUTE [P30CA014236] Funding Source: NIH RePORTER
- NATIONAL INSTITUTE OF BIOMEDICAL IMAGING AND BIOENGINEERING [T32EB001040, DP1EB016986, R01EB016963, R01EB006201] Funding Source: NIH RePORTER
- NATIONAL INSTITUTE OF NEUROLOGICAL DISORDERS AND STROKE [K08NS075144] Funding Source: NIH RePORTER
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Plasmonics-active gold nanostars exhibiting strong imaging contrast and efficient photothermal transduction were synthesized for a novel pulsed laser-modulated plasmonics-enhanced brain tumor microvascular permeabilization. We demonstrate a selective, optically modulated delivery of nanoprobes into the tumor parenchyma with minimal off-target distribution.
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