Journal
NANOSCALE
Volume 6, Issue 21, Pages 13242-13252Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/c4nr04258a
Keywords
-
Categories
Funding
- National Natural Science Foundation of China [21001072, 21231004, 21201117]
- Innovation Program of Shanghai Municipal Education Commission [13ZZ073]
- Science and Technology Commission of Shanghai Municipality [13NM1401100, 13NM1401101, 13DZ2292100]
- Shanghai Rising-Star Program [14QA1401800]
- State Key Laboratory of Rare Earth Resource Utilization [RERU2014012]
- Baoshan District Science and Technology Commission of Shanghai [bkw2013142]
Ask authors/readers for more resources
A series of new multifunctional nanomesoporous materials based on upconversion nanophosphors NaYF4:Yb, Tm@NaGdF4 (UCNPs) and lanthanide complexes were designed and synthesized through mesoporous capping UCNPs nanophosphors and linking lanthanide (Ln) complexes. The obtained UCNPs@mSiO(2)-Ln(dbm)(4) (Ln = Eu, Sm, Er, Nd, Yb) materials can achieve downconversion and upconversion luminescence to show multicolor emission (covering the spectral region from 450 nm to 1700 nm) under visible-light excitation and 980 nm excitation, respectively. In addition, low cytotoxicity and good biocompatibility was found as determined by methyl thiazolyl tetrazolium assay, and the nanomesoporous materials were successfully applied to cell imaging in vitro based on Eu3+ luminescence (under 405 nm excitation) and small animal imaging based on Tm3+ luminescence (under 980 nm excitation). The doped Gd3+ ion endows the nanomesoporous materials UCNPs@mSiO(2)-Ln(dbm)(4) with effective T-1 signal enhancement, which affords them as potential magnetic resonance imaging (MRI) contrast agents. Therefore, our results may provide more exciting opportunities for multimodal bioimaging and multifunctional applications.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available