Journal
NANOSCALE
Volume 6, Issue 21, Pages 12408-12413Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/c4nr03384a
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Funding
- National High-Tech R&D Program of China [2013AA032202]
- Science & Technology Commission of Shanghai Municipality [11nm0505100]
- National Natural Science Foundation of China [51203118]
- Fundamental Research Funds for the Central Universities
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A magnetothermally-responsive nanocarrier was developed for efficient thermo-chemotherapy by combining efficient magnetic hyperthermia (MH) and magnetothermally-facilitated drug release. The effective magnetothermal-response contributed to high enhancement of tumor cell killing by an operating mechanism involving MH-facilitated cellular uptake and Heat Shock Protein over-expression.
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