4.8 Article

Systemic gene silencing in plants triggered by fluorescent nanoparticle-delivered double-stranded RNA

Journal

NANOSCALE
Volume 6, Issue 17, Pages 9965-9969

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/c4nr03481c

Keywords

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Funding

  1. National Natural Science Foundation of China [31171399, 21174012]
  2. 973 Program [2012CB113900, 2013CB127603]
  3. Beijing Natural Science Foundation [2142026]
  4. Special Fund for Agro-scientific Research in the Public Interest [201003025]

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A cationic fluorescence nanoparticle efficiently enters plants with high transfection efficacy. Applying a mixture of G2/dsRNA to the model plant, Arabidopsis root, leads to significant reduction in the expression of important developmental genes and results in apparent phenotypes. This study reports a non-viral gene nanocarrier which triggers gene silencing in plants and leads to systemic phenotypes.

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