4.8 Article

An oligonucleotide-based label-free luminescent switch-on probe for RNA detection utilizing a G-quadruplex-selective iridium(III) complex

Journal

NANOSCALE
Volume 6, Issue 15, Pages 8489-8494

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/c4nr00541d

Keywords

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Funding

  1. Hong Kong Baptist University [FRG2/12-13/021, FRG2/13-14/008]
  2. Centre for Cancer and Inflammation Research, School of Chinese Medicine (CCIR-SCM, HKBU)
  3. Health and Medical Research Fund [HMRF/13121482]
  4. Research Grants Council [HKBU/201811, HKBU/204612, HKBU/201913]
  5. French National Research Agency/Research Grants Council [ANR-12-IS07-001-01, A-HKBU201/12]
  6. Nanobiotech Vibbnano program [ANR-10-NANO-04-03]
  7. Science and Technology Development Fund, Macao SAR [001/2012/A, 103/2012/A3]
  8. University of Macau [MYRG091(Y2-L2)-ICMS12-LCH, MYRG121(Y2-L2)-ICMS12-LCH]
  9. Mr. Kwok Yat Wai and Madam Kwok Chung Bo Fun Graduate School Development Fund

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We report herein the synthesis and application of a novel G-quadruplex-selective luminescent iridium(III) complex for the construction of an oligonucleotide-based, label-free, rapid and convenient luminescent RNA detection platform.

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