Journal
NANOSCALE
Volume 5, Issue 23, Pages 11362-11373Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/c3nr03861k
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Funding
- Royal Society
- Medical Research Council TSCRC [G0902411]
- UCL School of Life and Medical Sciences
- Medical Research Council [G1001539, MR/K026453/1] Funding Source: researchfish
- MRC [MR/K026453/1, G1001539] Funding Source: UKRI
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The use of human stem cells (SCs) in tissue engineering holds promise in revolutionising the treatment of numerous diseases. There is a pressing need to comprehend the distribution, movement and role of SCs once implanted onto scaffolds. Nanotechnology has provided a platform to investigate this through the development of inorganic magnetic nanoparticles (MNPs). MNPs can be used to label and track SCs by magnetic resonance imaging (MRI) since this clinically available imaging modality has high spatial resolution. In this review, we highlight recent applications of iron oxide and gadolinium based MNPs in SC labelling and MRI; and offer novel considerations for their future development.
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