Journal
NANOSCALE
Volume 5, Issue 18, Pages 8541-8549Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/c3nr02670a
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Funding
- National Talent Youth Science Foundation of China [60925018]
- National Natural Science Foundation of China [51002062, 61204015, 11174111, 61177042, 81201738]
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Rare-earth upconversion nanophosphors (UCNPs) have become one of the most promising luminescent materials for bio-applications, but their use still meets some limitations by difficulties in obtaining biocompatible UCNPs. To address this problem, we have developed a simple and versatile strategy for converting hydrophobic UCNPs into hydrophilic ones by amphiphilic silane modification with ultrathin thickness at room temperature (RT). In this strategy, the coating layers can also afford the place for loading with Eu(TTA)(3)(TPPO)(2) complex which displays down conversion luminescence (DCL). Due to the UC and DC properties, we achieved the dual mode physiological range temperature sensing and dual mode cell imaging. Such novel nanomaterials offer a new surface modification strategy for the NPs that are formed in the oil phase for bio-applications.
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