4.8 Article

Controllable and reproducible construction of a SERS substrate and its sensing applications

Journal

NANOSCALE
Volume 5, Issue 2, Pages 523-526

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/c2nr33350c

Keywords

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Funding

  1. NSFC [21171019, 21073203, 21103009]
  2. Beijing Natural Science Foundation [2122038]
  3. Fundamental Research Funds for the Central Universities [NCET-11-0584]

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A simple method for the preparation of a highly stable and reliable surface-enhanced Raman scattering (SERS) substrate was proposed. The SERS enhancement was demonstrated with good controllability and reproducibility through the controlled formation/deformation of SERS hotspots using a reversible DNA nanoswitch. Highly effective DNA detection was achieved using a well-designed sandwich structure.

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